Backpacking thru Italy?

I am going to Italy for 10 days with my husband and want to hit up as much of the country as possible. We'll be driving and I figured I'd start with Venice head due west to Cinque Terre, down south toward Florence and Rome and hopefully back up the other side. I know trying to fit it all in 10 days is going to drive me insane, but what do you suggest as far as funds, nightly hotels, gas prices, typical fees for museums, vineyards (VINO!), ferry rides, etc. Would Sicily be too far? (I would love to go there since I have family from there). I appreciate any and all help!